BDBM476549 2-[2-[[(8 endo)-3-(6-methylpyrimidin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl]amino]-5-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]-[1,2,4]triazolo[1,5-a]pyridin-8-yl]propan-2-ol::US10875854, Example 22

SMILES C[C@H](Oc1ccc(c2nc(N[C@H]3[C@H]4CC[C@@H]3CN(C4)c3cc(C)ncn3)nn12)C(C)(C)O)C(F)(F)F

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476549   

LigandPNGBDBM476549(US10875854, Example 22 | 2-[2-[[(8 endo)-3-(6-meth...)
Affinity DataEC50:  34.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
US Patent