BDBM476551 US10875854, Example 24::US10875854, Example 33

SMILES COc1cc(Nc2nc3c(ccc(O[C@@H](C)C(F)(F)F)n3n2)C(C)(C)O)ccc1-n1cnc(C)n1

InChI Key InChIKey=XTRVRSOEXQUNDQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476551   

LigandPNGBDBM476551(US10875854, Example 33 | US10875854, Example 24)
Affinity DataEC50:  39nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent

LigandPNGBDBM476551(US10875854, Example 33 | US10875854, Example 24)
Affinity DataEC50:  39nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent