BDBM476553 4-(3-chloro-1,2,4-triazol-1-yl)-3-methoxy-aniline::US10875854, Example 26

SMILES COc1cc(Nc2nc3c(ccc(O[C@@H](C)C(F)(F)F)n3n2)C(C)(C)O)ccc1-n1cnc(Cl)n1

InChI Key InChIKey=LUWIFBNXIUKPAK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476553   

LigandPNGBDBM476553(US10875854, Example 26 | 4-(3-chloro-1,2,4-triazol...)
Affinity DataEC50:  42.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent