BDBM476554 US10875854, Example 27

SMILES C[C@H](Oc1ccc(c2nc(Nc3ccc(c(c3)C#N)-n3cnc(C)c3)nn12)C(C)(C)O)C(F)(F)F

InChI Key InChIKey=MJTBKQHAXDHWPG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476554   

LigandPNGBDBM476554(US10875854, Example 27)
Affinity DataEC50:  37.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent