BDBM476555 8-isopropyl-N-((8 endo)-3-(2-methoxypyridin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl)-5-(((S)-1,1,1-trifluoropropan-2-yl)oxy)-[1,2,4]triazolo[1,5-a]pyridin-2-amine::US10875854, Example 28

SMILES COc1cc(ccn1)N1C[C@@H]2CC[C@H](C1)C2Nc1nc2c(ccc(O[C@@H](C)C(F)(F)F)n2n1)C(C)C

InChI Key InChIKey=XFPDZGOWXFBAOF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476555   

LigandPNGBDBM476555(US10875854, Example 28 | 8-isopropyl-N-((8 endo)-3...)
Affinity DataEC50:  19.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent