BDBM476562 N-[4-(4-chloroimidazol-1-yl)-3-methoxy-phenyl]-8-(trifluoromethyl)-5-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]-[1,2,4]triazolo[1,5-a]pyridin-2-amine::US10875854, Example 35

SMILES COc1cc(Nc2nc3c(ccc(O[C@@H](C)C(F)(F)F)n3n2)C(F)(F)F)ccc1-n1cnc(Cl)n1

InChI Key InChIKey=IQLVHLBDBCOJSE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476562   

LigandPNGBDBM476562(US10875854, Example 35 | N-[4-(4-chloroimidazol-1-...)
Affinity DataEC50:  31.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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