BDBM477695 (R)—N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxyazetidin-1-yl)-4-methyl-3,4-dihydro-1H-benzo[4,5]imidazo[2,1-c][1,4]oxazine-8-carboxamide::US10889571, Example 36

SMILES CNC(=O)c3cc(C(=O)Nc1ccc(OC(F)(F)Cl)cc1)cc4nc2COC[C@@H](C)n2c34

InChI Key InChIKey=RHFBMILGABCZCY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477695   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM477695(US10889571, Example 36 | (R)—N-(4-(chlorodifl...)
Affinity DataIC50: 0.370nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
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Date in BDB:
7/6/2025
Entry Details
US Patent