BDBM478040 US10889592, Compound I-18::US11325917, Compound I-18
SMILES C[C@H](CNC(=O)c1sc2nc(C)cnc2c1N)c1ccc(N2CC3CCC(C2)N3)c(c1)C#N
InChI Key InChIKey=IUDBVIYRVHSGCE-NLNFPOJYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 478040
Affinity DataIC50: 6.00E+3nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP28 Activity: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corni...More data for this Ligand-Target Pair