BDBM478955 N-(5-cyclopropy1-1H-pyrazol-3-yl)-2-(1'-methacryloyl-1',2',5',6'-tetrahydro- [2,3'-bipyridin]-5-yl)acetamide::US10894786, Comp. No 57

SMILES C=C(C)C(=O)N1CCC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1

InChI Key InChIKey=KKBGPXKESUWDQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478955   

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 478955BDBM478955(N-(5-cyclopropy1-1H-pyrazol-3-yl)-2-(1'-methacrylo...)
Affinity DataIC50: 10nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 478955BDBM478955(N-(5-cyclopropy1-1H-pyrazol-3-yl)-2-(1'-methacrylo...)
Affinity DataIC50: 140nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent