BDBM479301 US10894789, Compound 246

SMILES Cn1cc(-c2cccc(C(=O)Nc3nc(CCCCCC(=O)N4CCCCC4)cn3-c3ccccc3)c2)cn1

InChI Key InChIKey=PTANILSSAKZMOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 479301   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 479301BDBM479301(US12534452, Example 200)
Affinity DataIC50: 50nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent