BDBM480300 US10899738, Cpd. No 362::US10899738, Cpd. No 363::rac-4-((4-(3-((4-(2-(1H- imidazol-1-yl)-1-((1R,2S)-2- ((methylcarbamoyl)oxy) cyclopentyl)-1- phenylethyl)piperidin-1- yl)methyl)azetidin-1- yl)phenyl)sulfonyl)benzoic acid

SMILES CNC(=O)O[C@H]1CCC[C@@H]1C(Cn1ccnc1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccc(OC=O)cc2)CC1)c1ccccc1

InChI Key InChIKey=SHTSYVJEBIPJBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480300   

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM480300(rac-4-((4-(3-((4-(2-(1H- imidazol-1-yl)-1-((1R,2S)...)
Affinity DataIC50: 8nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM480300(rac-4-((4-(3-((4-(2-(1H- imidazol-1-yl)-1-((1R,2S)...)
Affinity DataIC50: 27nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent