BDBM480586 3-cyclopropyl-1-(3- (difluoromethyl)-2-(2- methylthiazol-5- yl)quinolin-5-yl)-5,7- dimethyl-7,8- dihydroimidazo[1,5-a] pyrazin-6(5H)-one::US10899769, Example 68
SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3cnc(C)s3)c(cc12)C(F)F
InChI Key InChIKey=ICUFVYYLUGJQPU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 480586
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 163nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 5nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair