BDBM480625 5,7-dimethyl-1-(7-methyl- 3-(1-methyl-1H-pyrazol-3- yl)isoquinolin-8-yl)-3- (tetrahydro-2H-pyran-4-yl)- 7,8-dihydroimidazo[1,5-a] pyrazin-6(5H)-one::US10899769, Example 104

SMILES Cc1ccc2cc(-c3cnn(C)c3)ncc2c1-c1nc(C2CCOCC2)n2c1CN(C)C(=O)C2C

InChI Key InChIKey=CJXAYERMOVPZCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480625   

TargetBromodomain-containing protein 4 [49-170](Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 480625BDBM480625(US10899769, Example 104 | 5,7-dimethyl-1-(7-methyl...)
Affinity DataIC50: 3.15E+3nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent

TargetCREB-binding protein [1081-1197](Human)
University Of Texas

US Patent
LigandChemical structure of BindingDB Monomer ID 480625BDBM480625(US10899769, Example 104 | 5,7-dimethyl-1-(7-methyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent