BDBM480931 8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-2-yl)ethyl]amino}pyrimidin-5-yl)methanone::US10906888, Example 145
SMILES C[C@H](Nc1ncc(cn1)C(=O)N1CCC2(C1)CCOCC2)c1cnccn1
InChI Key InChIKey=RZEQDKIIEMKNMN-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 480931
Affinity DataIC50: 0.242nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human plasma vanin-1 using pantetheine-7-amino-4-trifluoromethykournarin as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair