BDBM481216 3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4,3-c]azepine- 7,4'-tetrahydropyran]-1- yl)propyl acetate::US10906915, Ex. 6

SMILES CCc1nn(CCCOC(C)=O)c2CC3(CCOCC3)CNC(=O)c12

InChI Key InChIKey=XVGJOFRQGUPUNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481216   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Leo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 481216BDBM481216(3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4...)
Affinity DataIC50: 500nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent