BDBM483 (2S)-N-[(2S,3R)-4-[(tert-butylcarbamoyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide::(Hydroxyethyl)urea Isostere deriv. 11
SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(=O)NC(C)(C)C
InChI Key InChIKey=ZILOOGIOHVCEKS-HZFUHODCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 483
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University
Curated by ChEMBL
Washington University
Curated by ChEMBL
Affinity DataIC50: 6.01nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 6nMpH: 6.4 T: 25°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair