BDBM4830 1-[2-amino-6-(3,5-difluorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea::PD089828 analog 11

SMILES CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1cc(F)cc(F)c1

InChI Key InChIKey=AZETYZWGGZUSLG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4830   

TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4830(1-[2-amino-6-(3,5-difluorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50: 1.10E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4830(1-[2-amino-6-(3,5-difluorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50: 1.35E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4830(1-[2-amino-6-(3,5-difluorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50: 8.97E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article

TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4830(1-[2-amino-6-(3,5-difluorophenyl)pyrido[2,3-d]pyri...)
Affinity DataIC50: 8.97E+3nMpH: 7.4 T: 2°CAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article