BDBM483680 1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrrolo- [3,4-c]pyrrole- 2-carbonyl)-1H- 1H-pyrazole-3- carboxylic acid::US10927105, Ex 116::US11655217, Example 116

SMILES OC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2C1

InChI Key InChIKey=FNUFAXOEMKFZFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483680   

TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483680(1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483680(1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483680(1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483680(1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrr...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent