BDBM483721 1-(cis-5-(methyl(4- (trifluoromethyl)- benzyl)amino)- octahydrocyclopenta- [c]pyrrole-2- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 205::US11655217, Example 205

SMILES CN(Cc1ccc(cc1)C(F)(F)F)[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(n1)C(N)=O

InChI Key InChIKey=JTOQRURGTQJDEC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483721   

TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483721(US10927105, Ex 205 | 1-(cis-5-(methyl(4- (trifluor...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483721(US10927105, Ex 205 | 1-(cis-5-(methyl(4- (trifluor...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483721(US10927105, Ex 205 | 1-(cis-5-(methyl(4- (trifluor...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483721(US10927105, Ex 205 | 1-(cis-5-(methyl(4- (trifluor...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent