BDBM485044 US10934303, Cmpd No. 6d::US10934303, Example 4::US11285226, Compound 6d

SMILES OCCC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1)c1ccccc1

InChI Key InChIKey=UFPFMVPHDSUBQY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 485044   

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 93nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 93nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 93nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 262nMAssay Description:Binding affinity to GST-tagged ERalpha LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 262nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 262nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to GST-tagged ERRbeta LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to GST-tagged ERRalpha LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485044(US11285226, Compound 6d | US10934303, Example 4 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent