BDBM485047 US10934303, Cmpd No. 6g::US10934303, Example 10::US10934303, Example 11::US10934303, Example 7::US11285226, Compound 6g

SMILES CN1CCCC1CCOc1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(O)cc1

InChI Key InChIKey=ZUSXRJKXJTTXKD-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 485047   

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to GST-tagged ERRgamma LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 26nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 30nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 30nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 34nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 331nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 331nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 331nMAssay Description:Binding affinity to GST-tagged ERalpha LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human ERG measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 6.01E+3nMAssay Description:Binding affinity to GST-tagged ERRbeta LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to GST-tagged ERRalpha LBD (unknown origin) using fluorescein PGC1alpha as coactivator incubated for 1 hr by LanthaScreen TR-FRET co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485047(US10934303, Cmpd No. 6g | US10934303, Example 7 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent