BDBM485076 US10934303, Cmpd No. 38d::US10934303, Example 109

SMILES OCCC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN2CC3CC3[C@H]2CO)cc1)c1ccccc1

InChI Key InChIKey=UTNLGSPOQMFYKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 485076   

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485076(US10934303, Example 109 | US10934303, Cmpd No. 38d)
Affinity DataIC50: 83nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485076(US10934303, Example 109 | US10934303, Cmpd No. 38d)
Affinity DataIC50: 276nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485076(US10934303, Example 109 | US10934303, Cmpd No. 38d)
Affinity DataIC50: 8.80E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485076(US10934303, Example 109 | US10934303, Cmpd No. 38d)
Affinity DataIC50: 1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent