BDBM48563 2-phenyl-1H-quinolin-4-one::2-phenyl-4-quinolone::2-phenylquinolin-4-ol::CHEMBL277148::MLS000084697::SMR000019044::cid_161091

SMILES Oc1cc(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=JGABMVVOXLQCKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 48563   

TargetProcathepsin L(Human)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM48563(CHEMBL277148 | MLS000084697 | cid_161091 | SMR0000...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant cathepsin L expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM48563(CHEMBL277148 | MLS000084697 | cid_161091 | SMR0000...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM48563(CHEMBL277148 | MLS000084697 | cid_161091 | SMR0000...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of tubulin polymerization (ITP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM48563(CHEMBL277148 | MLS000084697 | cid_161091 | SMR0000...)
Affinity DataIC50: 6.40E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay