BDBM485939 US10946019, Example 43

SMILES CCc1c(C)nc(nc1Oc1ccc(cc1)C(O)=O)-c1ccccc1

InChI Key InChIKey=RJTYDGJPHZQFTP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485939   

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485939BDBM485939(US10946019, Example 43)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 485939BDBM485939(US10946019, Example 43)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of Nurr1-RXRalpha (unknown origin) heterodimer transfected in HEK293 cells co-transfected with pcDNA3 incubated for 16 hrs by Dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed