BDBM4868 1-(4-Chloroanilino)-4-(4-pyridylmethyl)-5,6,7,8-tetrahydrophthalazine::CGP79787 Analog 53::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-5,6,7,8-tetrahydrophthalazin-1-amine

SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3CCCCc23)cc1

InChI Key InChIKey=AUVPHBMIZZPXIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4868   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 4868BDBM4868(N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-5,6,7,8-...)
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 4868BDBM4868(N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-5,6,7,8-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed