BDBM487280 5-(1H-Indazol-5-yl)-3-(pyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::US10953012, Example 160

SMILES O=c1cc([nH]c2c(cnn12)-c1ccccn1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=FIMQJPWJJBZPQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 487280   

TargetCasein kinase II subunit alpha'(Human)
Bioenergenix

US Patent
LigandPNGBDBM487280(5-(1H-Indazol-5-yl)-3-(pyridin-2-yl)pyrazolo[1,5-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified CK2a2 (NP_001887; human full-length protein, GST tagged) from insect cells (final concentration 1.2 nM) is added to freshly prepared Base Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

LigandPNGBDBM487280(5-(1H-Indazol-5-yl)-3-(pyridin-2-yl)pyrazolo[1,5-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 3: In the presence of kinase and ATP, the Ulight-peptide is phosphorylated and captured by an anti-phospho-substrate antibody, which brings the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

LigandPNGBDBM487280(5-(1H-Indazol-5-yl)-3-(pyridin-2-yl)pyrazolo[1,5-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent