BDBM488062 2-((4-(2-((4-(4-(2- Methoxyethyl)piperazin-1- yl)phenyl)amino) pyrimidin-4-yl)-3-(pyridin- 3-yl-1H-pyrazol-1- yl)methyl)benzonitrile::US10954216, Example 82

SMILES COCCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(Cc3ccccc3C#N)nc2-c2cccnc2)cc1

InChI Key InChIKey=HZBSQQJOBJREEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488062   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488062(2-((4-(2-((4-(4-(2- Methoxyethyl)piperazin-1- yl)p...)
Affinity DataIC50: 9.20nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
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Date in BDB:
9/28/2021
Entry Details
US Patent