BDBM488580 US10961198, Compound 2.05::trans-N-(3-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)phenyl)- 4-hydroxy-N-((trans-4-(4-methoxy-3- methylphenyl)cyclohexyl)methyl)cyclohexanecarboxamide

SMILES COc1ccc(cc1C)[C@H]1CC[C@H](CN(C(=O)[C@H]2CC[C@H](O)CC2)c2cccc(c2)-c2cnn(CC(F)F)c2)CC1

InChI Key InChIKey=UIVAPHKVHKISKR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488580   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488580(US10961198, Compound 2.05 | trans-N-(3-(1-(2,2-Dif...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent