BDBM488843 2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3-(4- methylthiophen-2- yl)phenyl)-4-(2- fluoro-4- sulfamoylbenzyl)- 1H-pyrazol-1- yl)thiazole-4- carboxylic acid::US10961200, Compound 221

SMILES Cc1csc(c1)-c1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(NS(=O)=O)cc1F)-c1nc(cs1)C(O)=O

InChI Key InChIKey=ZBVROYRDWRTSAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488843   

TargetL-lactate dehydrogenase A chain(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM488843(US10961200, Compound 221 | 2-(5- (cyclopropylmethy...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent