BDBM490254 US10968215, Compound 128::US10968215, Compound 131

SMILES COc1cc(C)c(CNC(=O)c2cc3c(-c4ccccc4)ccn3c(C(C)N3CCC(N(C)C)CC3)c2C)c(=O)[nH]1

InChI Key InChIKey=GYWSPHQLIAMJCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490254   

LigandChemical structure of BindingDB Monomer ID 490254BDBM490254(US10968215, Compound 128 | US10968215, Compound 13...)
Affinity DataIC50: 100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 490254BDBM490254(US10968215, Compound 128 | US10968215, Compound 13...)
Affinity DataIC50: 100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent