BDBM492404 5-propyl[1,2,4]triazolo[1,5- alpyrimidin-7(4H)-one::US10975084, Example 8-6

SMILES CCCc1cc(=O)n2ncnc2[nH]1

InChI Key InChIKey=KZPRAIXAZRGXPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492404   

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492404(US10975084, Example 8-6 | 5-propyl[1,2,4]triazolo[...)
Affinity DataIC50: 4.76E+4nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetC-type lectin domain family 4 member M(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM492404(US10975084, Example 8-6 | 5-propyl[1,2,4]triazolo[...)
Affinity DataIC50: 2.36E+6nMAssay Description:Inhibition of human DC-SIGN overexpressed in human Raji cells incubated for 30 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed