BDBM493782 US10988459, Example 14
SMILES CN1c2ccccc2OC[C@H](NC(=O)c2nn(C)c3CC[C@H](Cc23)C(F)(F)F)C1=O
InChI Key InChIKey=XYJCKGKOLPUUIN-YPMHNXCESA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 493782
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of recombinant human His/GST-tagged RIPK1 (2 to 257 residues) expressed in insect expression system incubated for 2 hrs by fluorescence po...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1 [2-375](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 167nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1 [2-375](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: >1.00E+4nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair