BDBM49471 (E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)-2-propen-1-one::(E)-3-(3-methoxyphenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one::MLS000536709::SMR000155577::cid_5859537

SMILES COc1cccc(\C=C\C(=O)c2ccc[nH]2)c1

InChI Key InChIKey=AFIWQAOOUPKHRP-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 49471   

TargetCytochrome P450 1A2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human CYP1A2 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human CYP1B1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human CYP1A1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human CYP2D6 bound to yeast microsomal membrane using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate after 10 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataEC50:  1.49E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCytochrome P450 2C9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C19 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM49471(SMR000155577 | cid_5859537 | (E)-3-(3-methoxypheny...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP3A4 bound to yeast microsomal membrane using dibenzylfluorescein as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed