BDBM49532 (6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone::(6Z)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::2-(3-phenyl-5-isoxazolyl)phenol::MLS000570866::SMR000187290::cid_5343445

SMILES Oc1ccccc1-c1cc(no1)-c1ccccc1

InChI Key InChIKey=XWLIMTFPYMGWEB-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 49532   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataEC50:  1.79E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTumor necrosis factor receptor superfamily member 10B(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataEC50:  1.17E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49532((6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay