BDBM497244 7-((1R,4S)-4- hydroxycyclohexyl)-5-(1- (methylprolyl)piperidin-4- yl)-2-(((S)-pentan-2- yl)amino)-7H-pyrrolo[2,3- d]pyrimidine::US11001586, Example 16

SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)C1CCN(CC1)C(=O)C1CCCN1C

InChI Key InChIKey=FVMXIGRGLFHRDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497244   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM497244(7-((1R,4S)-4- hydroxycyclohexyl)-5-(1- (methylprol...)
Affinity DataIC50: 3nMAssay Description:Activity Against Mer Tyrosine Kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM497244(7-((1R,4S)-4- hydroxycyclohexyl)-5-(1- (methylprol...)
Affinity DataIC50: 750nMAssay Description:Activity Against Tyro3 Tyrosine Kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent