BDBM497302 (3,5-difluorophenyl)(4-(7- ((1r,4S)-4- hydroxycyclohexyl)-2- (((S)-pentan-2-yl)amino)- 7H-pyrrolo[2,3- d]pyrimidin-5-yl)piperidin- 1-yl)methanone::US11001586, Example 81

SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)C1CCN(CC1)C(=O)c1cc(F)cc(F)c1

InChI Key InChIKey=CFGDBDCIYYTKFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497302   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM497302((3,5-difluorophenyl)(4-(7- ((1r,4S)-4- hydroxycycl...)
Affinity DataIC50: 3nMAssay Description:Activity Against Mer Tyrosine Kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM497302((3,5-difluorophenyl)(4-(7- ((1r,4S)-4- hydroxycycl...)
Affinity DataIC50: 275nMAssay Description:Activity Against Tyro3 Tyrosine Kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent