BDBM499572 4-Methoxy-2-[4-(1'-methyl-6,6'-dioxo-1,6,1',6'-tetrahydro- [3,4']bipyridinyl-3'-yl)-pyrazol-1-yl]-benzonitrile::US11020380, Example 260

SMILES COc1ccc(C(O)=O)c(c1)-n1cc(cn1)-c1cn(C)c(=O)cc1-c1ccc(=O)[nH]c1

InChI Key InChIKey=HQGWOLKPNJJGSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499572   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM499572(4-Methoxy-2-[4-(1'-methyl-6,6'-dioxo-1,6,1',6'-tet...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent