BDBM499776 (2-chlorophenyl)(4-((cis-4-(3- hydroxyazetidin-1- yl)cyclohexyl)amino)-7H-pyrrolo[2,3- d]pyrimidin-5-yl)methanone::US11020398, Compound I-88

SMILES OC1CN(C1)[C@@H]1CC[C@@H](CC1)Nc1ncnc2[nH]cc(C(=O)c3ccccc3Cl)c12

InChI Key InChIKey=JHPFULRLUYLUKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499776   

TargetTyrosine-protein kinase BTK(Human)
Arqule

US Patent
LigandPNGBDBM499776((2-chlorophenyl)(4-((cis-4-(3- hydroxyazetidin-1- ...)
Affinity DataIC50: 2.5nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent