BDBM499790 N-(cis-4-((5-(2-chlorobenzoyl)-7H- pyrrolo[2,3-d]pyrimidin-4- yl)amino)cyclohexyl)-1- hydroxycyclopropane-1-carboxamide::US11020398, Compound I-102

SMILES OC1(CC1)C(=O)N[C@H]1CC[C@H](CC1)Nc1ncnc2[nH]cc(C(=O)c3ccccc3Cl)c12

InChI Key InChIKey=GOMHRDUKNCQZEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499790   

TargetTyrosine-protein kinase BTK(Human)
Arqule

US Patent
LigandPNGBDBM499790(N-(cis-4-((5-(2-chlorobenzoyl)-7H- pyrrolo[2,3-d]p...)
Affinity DataIC50: 1.90nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent