BDBM499857 (2-chloro-4-phenoxyphenyl)(4-((trans- 4-hydroxycyclohexyl)amino)-7H- pyrrolo[2,3-d]pyrimidin-5-yl)methanone::US11020398, Compound I-169

SMILES O[C@H]1CC[C@@H](CC1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12

InChI Key InChIKey=UUQPKXHDDOGEDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499857   

TargetTyrosine-protein kinase BTK(Human)
Arqule

US Patent
LigandPNGBDBM499857((2-chloro-4-phenoxyphenyl)(4-((trans- 4-hydroxycyc...)
Affinity DataIC50: 1.70nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
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Date in BDB:
11/28/2021
Entry Details
US Patent