BDBM50000287 2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL128444
SMILES Clc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1Cl
InChI Key InChIKey=GHCCBWMZKJQGLS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50000287
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]-U69593 from KOR in guinea pig brain membranes measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum) .using [3H]-U-69,593 a...More data for this Ligand-Target Pair
Affinity DataKi: 1.86E+3nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor mu 1 subtype in guinea pig brain (minus cerebellum) using [3H]-DAGO as radiol...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Zambeletti Research Laboratories
Curated by ChEMBL
Zambeletti Research Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor delta 1 subtype in guinea pig brain (minus cerebellum)using [3H]-DADLE as rad...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Kappa-opioid receptor agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair