BDBM50000570 3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL285250

SMILES CN1CCC2(CCCC1C2)c1cccc(O)c1

InChI Key

Data  10 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50000570   

TargetMu-type opioid receptor(Bovine)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards opioid receptor mu 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards opioid receptor mu 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  78nMAssay Description:Binding affinity towards Opioid receptor kappa 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  98nMAssay Description:Binding affinity towards opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  160nMAssay Description:Binding affinity towards opioid receptor kappa 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 169nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi:  200nMAssay Description:Binding affinity towards opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi: >500nMAssay Description:Binding affinity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataKi: >500nMAssay Description:Binding affinity towards Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 557nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 911nMAssay Description:Inhibition of [3H]U-69593 radioligand binding to Guinea pig opioid receptor kappa 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(CHEMBL285250 | 3-(2-Methyl-2-aza-bicyclo[3.3.1]non...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed