BDBM50000580 5-[7-(4-Hydroxy-piperidin-1-yl)-heptyloxy]-2-phenyl-chromen-4-one::CHEMBL38294

SMILES OC1CCN(CCCCCCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1

InChI Key InChIKey=AMINWDBXDFTOJB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000580   

TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000580(CHEMBL38294 | 5-[7-(4-Hydroxy-piperidin-1-yl)-hept...)
Affinity DataIC50: 36nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000580(CHEMBL38294 | 5-[7-(4-Hydroxy-piperidin-1-yl)-hept...)
Affinity DataIC50: 65nMAssay Description:Potency at the sigma binding site was determined in radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50000580(CHEMBL38294 | 5-[7-(4-Hydroxy-piperidin-1-yl)-hept...)
Affinity DataKi:  2.40E+3nMAssay Description:Affinity towards dopamine receptor D2 was determined by competition studies using [3H]sulpiride in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed