BDBM50000776 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperazine::CHEMBL70807

SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1

InChI Key InChIKey=LUKGVLGXYXKAAS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000776   

TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000776(CHEMBL70807 | 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000776(CHEMBL70807 | 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-...)
Affinity DataKi:  1.20nMAssay Description:Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000776(CHEMBL70807 | 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity against dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed