BDBM50000896 Acetic acid 2-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-ethyl ester::CHEMBL89876

SMILES CC(=O)OCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=IYFJFKYCOWHMMW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000896   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000896(Acetic acid 2-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000896(Acetic acid 2-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]...)
Affinity DataEC50:  870nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed