BDBM50001265 3-(4-Amino-phenyl)-5,7-dichloro-4-hydroxy-1H-quinolin-2-one::CHEMBL116733

SMILES Nc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O

InChI Key InChIKey=HTKYXIJVOMESER-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001265   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(CHEMBL116733 | 3-(4-Amino-phenyl)-5,7-dichloro-4-h...)
Affinity DataKi:  18nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(CHEMBL116733 | 3-(4-Amino-phenyl)-5,7-dichloro-4-h...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed