BDBM50001375 1'-[7,7-dimethyl-2-oxo-(1S,4R)-bicyclo[2.2.1]hept-1-ylmethylsulfonyl]-1-methylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL340465

SMILES CN1C(=O)C2(CCN(CC2)S(=O)(=O)C[C@]23CCC(CC2=O)C3(C)C)c2ccccc12

InChI Key InChIKey=HPLLFPMXQQRORV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001375   

TargetOxytocin receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001375(CHEMBL340465 | 1'-[7,7-dimethyl-2-oxo-(1S,4R)-bicy...)
Affinity DataIC50: 6.50E+3nMAssay Description:Half-maximal inhibition of binding of [3H]oxytocin to OT receptor in rat uterine tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a/V1b/V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001375(CHEMBL340465 | 1'-[7,7-dimethyl-2-oxo-(1S,4R)-bicy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Half-maximal inhibition of binding of [3H]- vasopressin to the vasopressin receptor 2 in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a/V1b/V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001375(CHEMBL340465 | 1'-[7,7-dimethyl-2-oxo-(1S,4R)-bicy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Half-maximal inhibition of binding of [3H]vasopressin to vasopressin receptor 1 in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed