BDBM50001378 1'-(4-nitrobenzylsulfonyl)spiro[1H-indene-1,4'-(hexahydropyridine)]::CHEMBL338814

SMILES [O-][N+](=O)c1ccc(CS(=O)(=O)N2CCC3(CC2)C=Cc2ccccc32)cc1

InChI Key InChIKey=LJHUQNNGWZZXCW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001378   

TargetVasopressin V1a/V1b/V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001378(CHEMBL338814 | 1'-(4-nitrobenzylsulfonyl)spiro[1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Half-maximal inhibition of binding of [3H]vasopressin to vasopressin receptor 1 in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxytocin receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001378(CHEMBL338814 | 1'-(4-nitrobenzylsulfonyl)spiro[1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Half-maximal inhibition of binding of [3H]oxytocin to OT receptor in rat uterine tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a/V1b/V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001378(CHEMBL338814 | 1'-(4-nitrobenzylsulfonyl)spiro[1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Half-maximal inhibition of binding of [3H]- vasopressin to the vasopressin receptor 2 in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed