BDBM50001644 6-(4,6-Diphenyl-pyridin-2-yloxy)-2,2-dimethyl-hexanoic acid::CHEMBL135671

SMILES CC(C)(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=KPQMGPINRWJVQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001644   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001644(CHEMBL135671 | 6-(4,6-Diphenyl-pyridin-2-yloxy)-2,...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001644(CHEMBL135671 | 6-(4,6-Diphenyl-pyridin-2-yloxy)-2,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001644(CHEMBL135671 | 6-(4,6-Diphenyl-pyridin-2-yloxy)-2,...)
Affinity DataIC50: 160nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed