BDBM50001645 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2-methyl-hexanoic acid::CHEMBL344230

SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O

InChI Key InChIKey=XHRNNMAQJJKUCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001645   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(CHEMBL344230 | 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(CHEMBL344230 | 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(CHEMBL344230 | 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 70nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed